Cell Fractionation smooth microsome fraction guinea pig pancreas

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Medical Historical Library, Cushing/Whitney Medical Library > Cell Fractionation smooth microsome fraction guinea pig pancreas

15817832

Description

Title: Cell Fractionation smooth microsome fraction guinea pig pancreas
Creator: Jamieson, James D
Contributor: Jamieson, James D
Published / Created: 5/1/1961
Publication Place: New Haven, CT
Publisher: Yale University School of Medicine
Description: 3.25 in. x 4 in. Lantern Slides
Cell fractionation confirmed that newly synthesized acinar cell secretory proteins moved from the RER to the periphery of the Golgi in the lumen of a smooth-surfaced membrane bounded compartment. This paper also describes the pancreatic slice system and the pulse-chase protocol used to label newly synthesized secretory proteins with radioactive leucine. The micrograph shows smooth microsomes obtained from the top band in the photograph of sucrose density gradient.
Original Magnification: x10,000
Extent: 3.25 in. x 4 in.

Access: Public
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Yale Community Only
Citation: See Jamieson, J.D., and Palade, G.E. Intracellular transport of secretory proteins in the pancreatic exocrine cell. I. Role of the peripheral elements of the Golgi complex. J. Cell Biol. 34:577-596, 1967.