3.25 in. x 4 in. Lantern Slides and Classic TEM. First description of the endoplasmic reticulum. Whole mount of unfixed, dried chick embryo fibroblast. The genius of their approach was to grow embryonic chick cells on a thin collodion film supported by a fine mesh copper grid. After the cells had grown and spread out thin processes, the preparation was air dried. They reasoned that the thin processes would allow electrons to penetrate in the electron microscope. The only microscope available to them was owned by the Interchemical Corp. and housed in the Empire State Building. Fullam was the technician. The electron microscope was a first generation RCA type B.
3.25 in. x 4 in. Lantern Slides, Chlamydomonas, a single-cell alga, was extensively used in the Siekvevitz/Palade laboratories at the Rockefeller to study chloroplast membrane biogenesis. These organisms could be grown in large cultures in the dark then, when exposed to light, rapidly and synchronously developed chloroplasts. "Clammys" also grew freely in our buffer and distilled water jugs in all of the labs!, and Original Magnification: x43,000
